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Bullboard - Stock Discussion Forum
Allakos Inc
ALLK
Healthcare
Biotechnology
Allakos Inc. is a clinical-stage biotechnology company, which is engaged in the development of therapeutics that target immunomodulatory receptors present on immune effector cells involved in allergy, inflammatory and proliferative diseases. The Company’s most advanced product candidate, AK006, is in a Phase I clinical trial. AK006 targets Siglec-6, an inhibitory receptor expressed selectively...
on mast cells. It is developing AK006 for the treatment of CSU and potentially other indications. AK006 has completed preclinical testing, and in these studies, it has demonstrated that binding of AK006 to Siglec-6 inhibits multiple modes of mast cell activation, including IgE, IL-33, KIT, C5a and MRGPR-X2. In addition to mast cell inhibition, AK006 reduced human tissue mast cells via ADCP in the presence of activated macrophages. The Company is also developing lirentelimab (AK002) and, in conjunction with the Phase II, lirentelimab results in atopic dermatitis and chronic spontaneous urticaria.
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Bullboard (NDAQ:ALLK)
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whytestocks
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Post by
whytestocks
on Feb 26, 2024 4:00pm
Allakos Presents Preclinical Data Highlighting Inhibition of
News; $ALLK Allakos Presents Preclinical Data Highlighting Inhibition of MRGPRX2-Mediated Mast Cell Activation with AK006 at AAAAI 2024@ Atopic dermatitis and prurigo nodularis skin lesions show
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AviseAnalytics
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AviseAnalytics
on Jan 10, 2022 7:47am
SHOULD ALLAKOS INC BE ON YOUR INVESTMENT WATCHLIST?
$ALLK Allakos Inc. (NASDAQ:ALLK), a clinical-stage biopharmaceutical company developing therapeutic monoclonal antibodies for treatment of inflammatory, and proliferative diseases, faced a
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