Misinformation spreading so let me out this right away. 

ATB-429 parent moeity is Mesalamine.  ATB-346 (Otenaproxesul) parent is Naproxen.  

In last AME with 42 participants, 3/42 expected with LTE, when 5/42 observed with parent Naproxen.  

All claims about long-term intolerability of ATB-429 for IBD are false.  Lots of evidence to show Mesalamine is tolerated well long-term in IBD and adding H2S may improve mucosal healing properties without any significant adverse effects based on H2S insights from ATB-346. 


Edou111 wrote:
If this can't be tolerated on a long period of time, why are we talking H2S for IBD ???