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Isotechnika Pharma Inc IPHAF



GREY:IPHAF - Post by User

Bullboard Posts
Comment by snrkidon Apr 28, 2009 9:54am
286 Views
Post# 15949279

RE: excellent !

RE: excellent !Safety seems to be confirmed same as Canadian trials.  Efficacy at safe dosing is good.  Cyclo dosing was very high and that is why better data. 

Would you prefer safety vs. slightly more efficacy with side effects like renal damage?   I think the answer is safety.

happy trading...
snrkid

   The table below summarizes the most important adverse events over 60
    weeks.

    Adverse Event                           Voclosporin      Cyclosporine
    Hypertension                                9.4%             14.7%
    Headache..                                    7.3%             12.4%
    Paraesthesia                                0.8%              7.0%
    Nausea       ....                               3.4%              6.2%
    Nasopharyngitis                           2.9%              6.2%
    Blood Creatinine Increased       2.3%              5.4%
    Fatigue                    .......                 2.6%              5.4%
    Hair Growth Abnormal                  0.3%              3.9%
    Blood Urea Increased                  0.3%              3.1%
    Muscle Spasms                             0.8%              3.1%
    Diarrhea                           .......         4.4%              2.3%

    "ESSENCE has confirmed the previous safety and efficacy data from our
Canadian Phase 3 trial", explains Dr. Foster. "We believe that it provides an
essential addition to the armamentarium of Dermatologists to treat this
debilitating disease. Our objective was to show that voclosporin is of
significant value to patients and physicians and provides a serious treatment
alternative."
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