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Theralase Technologies Inc. V.TLT

Alternate Symbol(s):  TLTFF

Theralase Technologies Inc. is a Canada-based clinical-stage pharmaceutical company. The Company is engaged in the research and development of light activated compounds and their associated drug formulations. The Company operates through two divisions: Anti-Cancer Therapy (ACT) and Cool Laser Therapy (CLT). The Anti-Cancer Therapy division develops patented, and patent pending drugs, called Photo Dynamic Compounds (PDCs) and activates them with patent pending laser technology to destroy specifically targeted cancers, bacteria and viruses. The CLT division is responsible for the Company’s medical laser business. The Cool Laser Therapy division designs, develops, manufactures and markets super-pulsed laser technology indicated for the healing of chronic knee pain. The technology has been used off-label for healing numerous nerve, muscle and joint conditions. The Company develops products both internally and using the assistance of specialist external resources.


TSXV:TLT - Post by User

Bullboard Posts
Comment by cytochromeon May 13, 2016 3:21pm
162 Views
Post# 24871677

RE:RE:RE:RE:RE:Cytochrome's

RE:RE:RE:RE:RE:Cytochrome's Awwwwwww.......poor Google Bencro.....just can't get enough of my insightful knowledge. So yet again I will have to spell out his misconceptions:

1. 905 nm may go deeper but there is evidence to suggest this may not be true (see Anders below). 

COMPARISON OF LIGHT PENETRATION OF 810 nm AND 904 nm WAVELENGTH LIGHT IN ANESTHETIZED RATS J. Anders, X Wu USUHS Bethesda, USA It has been reported that 20 % of the output power of 810 nm wavelength light penetrated through rat skin and remained stable over a 150 sec irradiation period while there was an increase in light penetration of 904 nm wavelength super-pulsed light over the 150 sec ( Photomed Laser Surg (2012; 12: 688–94.). The purpose of this study was to reexamine the penetration of these wavelengths of light. The lasers used were: 808 nm wavelength (B&W Tek) (output power 1 W, CW) and 904 nm wavelength superpulsed (Irradia) (20 W, mean output power 60 mW, 5 kHz).The power density was measured by a near infrared detector (B&W Tek, Inc). An incision was made through the skin and gastrocnemius muscle of anesthetized rats. The detector was placed under the muscle or skin. Experiments were done on laser emission stability. Once stability was reached, data were collected at 0, 10, 30 sec and every 30 sec for a total of 4 minutes. The 904 nm wavelength laser required 10 minutes to stabilize. If power density measurements were taken during this time, light penetration appeared to increase over time of irradiation. This increased penetration was eliminated once the output reached stability. The percentage of light transmission through the skin was: 808 nm laser=24.63 %, 904 nm laser=19.94 % and skin and muscle: 808 nm laser=7.24 %, 904 nm laser=4.01 %. Based on these data, penetration of 810 nm wavelength light through tissue is greater than super-pulsed 904 nm wavelength light.

2. Jan Bjordal is completely respected in the field of LLLT. In fact, he is one of the best. His research has looked at several wavelengths not just 904/905 nm. Don't believe me? Search on PubMed and look for yourself. I can't say the same about Mandel. He's a Russian MD and last I checked, wasn't licensed to practice in Ontario (hmmmmm.......isn't that a no no to run around with an MD after your name if your not licensed to practice????) Mandel is not a fixture in LLLT research and is a hired gun not an unbiased researcher like Tiina Karu, etc. He has no credibility in LLLT...maybe other research areas??? 

3. Again and again and again (as I bang my noggin against the wall), the goal is to stimulate CCO (that's cytochrome C oxidase) which relates to the action spectra of the enzyme. And Google Bencro, surely you know by now what the peak absorption action spectra are after my repeated posts from Tiina karu's research...right??? I guess not, so here they are, yet again (notice the absence of 904/5 nm wavelength).

The peak positions are between 613.5 and 623.5 nm (in one spectrum, at 606 nm), in the red maximum. The far-red maximum has exact peak positions between 667.5 and 683.7 nm in different spectra. Two near infrared maxima have peak positions in the range 750.7–772.3 nm and 812.5–846.0 nm, respectively. Karu and Kolyakov Exact Action Spectra for Cellular Responses Relevant to Phototherapy

4. In response to this:

  • 660 nm absorbed by superficial tissue clears the way for infrared 875 nm to penetrate deeper and eliminate cellular interferencewhich allows infrared 905 nm super pulsed laser to go even deeper: up to 4-5 inches.

Really??? 660 nm "clears the way"........that sounds so scientific it must be true. And the fact it was stated by a competitor manufacturer surely means it must be true!! bahahahahahahahaha

5. Lastly, I keep telling you Google Bencro (notice the loss of your former honourary title)...superpulsed is alright for LLLT .....just not the right choice for optimal results. See 95+% of research on LLLT that uses 630-660 nm and 780-840 nm for the optimal wavelengths. The TLC2000 is certainly not some kind of breakthrough laser pain technology that all your koolaid hooligans are cheering about. 
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