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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Healthcare
Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Antibe Therapeutics Inc(Pre-Merger)
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Comment by WatchLearnEarnon Mar 20, 2018 10:46pm
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Post# 27750933

RE:this is what its all about not GI safety

RE:this is what its all about not GI safetyHaha, every single person who bought this and pushed the SP up to a new 52wk high today knows about the Phase 1 issues. Antibe didn't realize how STRONG their drug was, one. And two, two people LIED to get into the clinical trial who had Hepatitis C and it was those two subjects who had the adverse reactions! Duh!

Antibe had an independent 3rd party re-examine all the trial documentation, clinical trial execution and final results and HEALTH CANADA approved the Ph. 2 trial which was an indisputable success.

So shut the fkk up and buy the ask you scum.

BlueCielo wrote: Additional liver enzyme elevations were observed in other subjects in the higher dose cohorts.  The Company is concerned that, when assessed together, these liver enzyme elevations are indicative of potential hepatotoxicity.  Pre-clinical studies on ATB-346 had provided no indication of potential hepatotoxicity at therapeutic doses. 


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