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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

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Post by jordon3on Apr 18, 2018 1:10pm
149 Views
Post# 27905552

ICG

ICG

Patent filed for cannabis-based Alzheimer’s treatment

   
 
Click to enlargeCannabis is medicine. As the use of medicinal cannabis becomes a fact of life in not only North America, but the world, it is now widely recognized that cannabinoids (the active ingredients in the cannabis plant) have numerous medicinal applications.

Many cannabis companies are producing dried flower and related products for use as medicine, and more and more often, these products are being officially prescribed by licensed physicians. This is greatly beneficial to the patients using medicinal cannabis as well as being profitable for cannabis companies.

How do investors see the profits from such cannabinoid medications increase? Through patent protection. The “Patent Cliff” is an operational and financial nightmare for the pharmaceutical industry. In 2017 alone; Big Pharma faced the loss of patent protection on licensed drugs with total revenues of $26.5 billion.

These multinational drug companies have never been hungrier for new patent-protected drugs, to replenish their drug pipelines – and their bottom lines. As drug development costs soar, more and more often Big Pharma is choosing to buy patent-protected drugs rather than meeting those development needs organically.

One Company that is looking to cash-in on the opportunities presented by the Patent Cliff is India Globalization Capital Inc. (NYSE Market: IGCForum). IGC describes itself as a “cannabis pharmaceutical company”, entering the cannabis space in 2013. On April 10, 2018, the Company announced the filing of its eighth U.S. patent application.

India Globalization Capital has pioneered the development of Hyalolex, a cannabinoid-based treatment aimed at alleviating many of the symptoms suffered by Alzheimer’s patients. A drug industry publication from October 2017 predicts sales of Alzheimer’s disease treatments to reach $14.8 billion by 2026.

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