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Aphria Inc. APHA

Aphria, which is headquartered in Ontario, produces and sells medicinal and recreational cannabis. The company operates through retail and wholesale channels in Canada and internationally. Aphria is a main distributor of medical cannabis to Germany and has operations in over 10 countries outside of Canada. However, it does not have exposure to the U.S. CBD or THC markets due to the constraints of federal prohibition. It has some U.S. exposure through the acquisition of SweetWater, a craft brewer


NDAQ:APHA - Post by User

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Comment by GreenNmeon Nov 30, 2018 10:05pm
77 Views
Post# 29048548

RE:RE:TBD & health cda cannabis vs fentanyl

RE:RE:TBD & health cda cannabis vs fentanylAgreed, when you say oral capsules will not be the fastest acting. But that's about the only part of your statement I agree with. Coming from someone who has had an opioid prescription for 9 years, and has been smoking weed daily for about 20 years...I can lend credible feedback. I wouldn't go as far as saying oral mj pills will NEVER be as effective in relieving severe pain...bc there are times when I can take 3 of my pills for my back pain, but what ultimately gives me the relief I seek, was that joint that knocked me on my aass and let me get some sleep. Could I just use mj? No, i cant. Not currently with what's available. But in the future I believe they'll be able to extract a high potency THC/ CBD mix that can be really good for my back pain so I can take way less of the opioids. Thc and CBD are just 2, there are tons more cannabinoids in the plant we really dont know much about but we are starting to find out in research. I remain hopeful on the medical aspects bc it has helped me personally for years. Tbh it's often the combination of my pills and mj that gives the best relief for my pain, not just one or the either. So while mj pills might not completely replace opioids, they can work along side them cutting down a lot on the opioid usage.
Earlylnvestor59 wrote: These are the type of posts i read when the crypto bubble bursted and all share prices plummeted... Investors were so desperate they started bringing up old NR's to convince others to buy... Weed has only been legal for one month and I'm already seeing the same pattern.. On top of that weed will never be as effective as any opioid for relieving severe pain and suffering and this trial is stupid as an oral capsule will never be as strong and will most certainly not be a  faster acting alternative than a sublingual strip or a needle straight to the bloodstream...  

gottahunch wrote:
Did anyone see this NR from August on TBD's site? I think there is massive opportunity with this company and Vic is going to knock it out of the park with pharma. Pieces coming together. Shorts, you've been warned. Health Canada Gives Green Light to Tetra Bio-Pharmas Cannabis Vs. Fentanyl Trial 09 August, 2018 Patient recruitment to begin for landmark research ORLEANS, Ontario, Aug. 09, 2018 (GLOBE NEWSWIRE) -- Tetra Bio-Pharma Inc., a leader in cannabinoid-based drug discovery and development (TSX VENTURE: TBP) (OTCQB: TBPMF), is pleased to announce that Health Canada has approved its protocol for a clinical trial investigating its PPP001 drug as an alternative to the opioid fentanyl in the management of breakthrough cancer pain. The clinical trial will be conducted by Montreal-based Sant Cannabis, a medical clinic and contract research organization specialized in clinical research for cannabis - based therapies. The trial will assess the time-to-relief in patients suffering from breakthrough cancer pain. Based on its clinical data, Tetra believes that the pharmacodynamic properties of PPP001 may provide a novel faster acting alternative to the opioid fentanyl. In addition, the time-to-maximal plasma concentrations of THC suggest that PPP001 will provide rapid relief to the patients suffering. As a prescription drug with a Drug Identification Number (DIN) PPP001 will be eligible for insurance coverage, making the cannabis-based medication accessible in pharmacies thereby providing much easier access. The Opioid Crisis There have been numerous news reports in the North America media highlighting the fact that we are experiencing an opioid crisis. In June, the Canadian government asked drug makers to stop marketing opioids, but for patients suffering from uncontrolled pain, this news does not provide them with an alternative to alleviate their pain. There were 41,997 opioid-related deaths in the USA in 2016 contributing to the U.S. Presidents declaration that the U.S. is experiencing an opioid crisis. 92% of the 3,987 apparent opioid-related deaths in Canada in 2017 were accidental. Males make up 76% of these fatalities; more than one-third among those aged 30-39. The percentage of these accidental deaths involving fentanyl rose from 55% in 2016 to 72% in 2017. Medical cannabis may help reduce the use of drugs like fentanyl for treating breakthrough and chronic pain. However, unrefuted scientific data on its safety and effectiveness that will satisfy regulators, professional groups and insurers is whats missing, said Dr. Guy Chamberland, Interim CEO and Chief Scientific Officer of Tetra Bio-Pharma. Tetra is in the business of providing that evidence which would see our drug PPP001 become a complementary prescription therapy. Weve taken a pharmaceutical pathway of drug development involving collaborative dialogue with Health Canada and the FDA to bring cannabis and cannabinoid products to market so that physicians, who have been hesitant to recommend it, will have a new, trusted therapeutic option for their patients. Cannabis versus Fentanyl Clinical Trial Recruitment Sant Cannabis will begin recruitment for the clinical trial as of October 2018. More information on eligibility criteria as well as the details and duration of the trial can be obtained by visiting the Sant Cannabis website: www.santecannabis.ca/en/research/cannabis-clinical-trial/ or by calling 514-419-4131 and select English and press 5 to reach the research team. A bout Tetra Bio-Pharma Tetra Bio-Pharma (TSX-V: TBP) (OTCQB: TBPMF) is a biopharmaceutical leader in cannabinoid-based drug discovery and development with a Health Canada approved, and FDA reviewed, clinical program aimed at bringing novel prescription drugs and treatments to patients and their healthcare providers. The Company has several subsidiaries engaged in the development of an advanced and growing pipeline of Bio Pharmaceuticals, Natural Health and Veterinary Products containing cannabis and other medicinal plant-based elements. With patients at the core of what we do, Tetra Bio-Pharma is focused on providing rigorous scientific validation and safety data required for inclusion into the existing bio pharma industry by regulators, physicians and insurance companies. For more information visit: www.tetrabiopharma.com About Sant Cannabis Established in Montreal, Quebec in 2014, Sant Cannabis is a Centre of Excellence in medical cannabis research, clinical practice and healthcare professional training. Since its inception, Sant Cannabis has provided medical assessment, education, monitoring and follow-up to 5,000 patients referred by more than 2,000 Quebec physicians. Sant Cannabis operates within the guidelines for the authorization of medical cannabis as set out by the Collge des mdecins du Qubec. As an independently credentialed clinical trial research organization, and with unparalleled clinical experience supporting both patients and healthcare professionals, Sant Cannabis has established itself as a global leader in medical cannabis research. Sant Cannabis is currently conducting a Health Canada approved Phase 3 trial for PPP001 for advanced cancer patients suffering from uncontrolled pain and associated symptoms, as well as a Phase 2 trial for PPP005 investigating the use of oral capsules of cannabis oil for the treatment of chronic pain. For more information visit: www.santecannabis.ca Source: Tetra Bio-Pharma Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release. Forward-looking statements Some statements in this release may contain forward-looking information. All statements, other than of historical fact, that address activities, events or developments that the Company believes, expects or anticipates will or may occur in the future (including, without limitation, statements regarding potential acquisitions and financings) are forward-looking statements. Forward-looking statements are generally identifiable by use




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