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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Bullboard Posts
Comment by bfwon Dec 12, 2018 4:21pm
162 Views
Post# 29105767

RE:RE:RE:RE:RE:RE:ViiV Presentation in London - fostemsavir

RE:RE:RE:RE:RE:RE:ViiV Presentation in London - fostemsavirI wrote this a while ago:

Lots to digest.

A few comments after a quick review.

(1) Viiv was very brief in their discussion of meeting their primary endpoint. That makes me think they were not particularly  impressed with the results

(2)Fostemsavir led to 64% having > 0.5 log reduction in HIV RNA at Day 8. Trogarzo achieved that target in 83%. Were Trogarzo patients also sicker at baseline?

(3)Trogarzo achieved mean viral load reduction at 24 weeks of 3.1 log. Fostemsavir was 2.29 log and did not get better even at 48 weeks.

(4) Most patients that received Fostemsavir had at least one adverse event. It seems like Trogarzo is likely better tolerated.

Anyway, I guess we can’t see what proportion of patients in this study were on Trogarzo as well.

I don’t think I see a big threat especially given Trogarzo’s head start.

bfw

Read more at https://www.stockhouse.com/companies/bullboard/t.th/theratechnologies-inc?postid=28911569#FCytOHYlWTS8zpsL.99
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