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Claritas Pharmaceuticals Inc V.CLAS.H

Alternate Symbol(s):  CLAZF

Claritas Pharmaceuticals, Inc., formerly Kalytera Therapeutics Inc, is a biotechnology company that is focused on developing R-107 for the treatment of vaccine-resistant coronavirus disease (COVID) strains. The Company’s products in development include R-107 for coronavirus disease and Viral Infections, R-107 and Vaccines, and CLA-1816 for treatment of pain. R-107 is designed to defeat COVID viruses on contact. R-107 targets the Achilles heel of COVID, the spike protein on the surface of the virus. R-107 releases nitric oxide, which attaches to a specific amino acid on the spike protein, thereby disabling the spike protein. The CLA-1816 provides effective pain reduction, without the risks of addiction or respiratory suppression that exist with opioid analgesics. CLA-1816 strongly binds with and activates the alpha3 glycine pain receptor in the spine. The Company has leased a laboratory, office, and archival space in Beverly, Massachusetts.


TSXV:CLAS.H - Post by User

Comment by MinimumDamageon Mar 04, 2021 12:41pm
102 Views
Post# 32715947

RE:RE:Explains it best.

RE:RE:Explains it best. AngelaL - (3/4/2021 11:29:43 AM)
RE:Explains it best.
I am not familiar with the company's past but there is a strong record of accomplishment and achievement for their main technology, R-107. The drug has shown excellent benefit in large animal models of acute lung injury (PR from last summer) and has completed a full battery of required preclinical studies (PR last summer) and is now about to enter Phase 1 clinical trials. The Comp has wisely refocused its energy on a world-class technology targeting the Covid pandemic. I will not be surprised if we hear soon of clinical trial start and further progress.

 

Even though R-107 has shown excellent benefits for acute lung injury, Kalytera only holds rights to R-107 for the treatment of coronaviruses and COVID-19 infection. In turn, due to the cancelled acquisition, Salzman has retained all rights for CILI, and PAH and everything else where acute lung injuries could be treated.
For the company's past, their main program GVHD has been forfeited and turned back to the Israeli group Talent they bought if off of to free themselves of all liabilities. As you can suspect, it was a great dissapointment for shareholders since the data showed that the product worked in the prevention of GVHD. Reasons were the cost of phase three which would require a larger pharma company taking the project over and, lacking the large market size they require as well as the CBD association made it a less than attractive opportunity for them.
 

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