GREY:ATBPF - Post by User
Comment by
Straylighton Mar 25, 2021 12:15pm
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Post# 32875688
RE:Expensive Pfizer drug for OA likely to fail
RE:Expensive Pfizer drug for OA likely to failNice article. Couple good quotes about that drug from the link:
"Although FDA said tanezumab proved to be effective, its effect size “is modest, and there is no convincing evidence of a superior efficacy of tanezumab over NSAIDs.”
"In addition, the agency said tanezumab is associated with an elevated risk of requiring a total joint replacement, as observed in two of the three post-2015 clinical studies, with evidence of dose response. There is also evidence that the risk for developing joint destruction is 2- to 3-fold higher if NSAIDs and tanezumab are used together, FDA said."