Theratechnologies Inc T.TH

Alternate Symbol(s): THTX

Healthcare Biotechnology

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.

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Comment by jeffm34on Nov 12, 2021 2:51pm

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Post# 34121053

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:Credit Suisse event now available

What aren't you understanding? I'll get out my crayons and draw you a picture. You are touting the drug to treat lipodystropy. That's it!!!! The fact that it may prevent NASH is secondary to the issue.

qwerty22 wrote:

That is illegal. You can't tout the drug as treating NASH. Maybe you can point a doctor to Grinspoon's work and allow them to draw their own conclusions but you can't sell that idea. You also can't expect doctor to necessarily draw these conclusion independently. Treatment has guidelines and doctor follow the professional standards. I think they can only approach this tangentially. Here is an example I stumbled on yesterday.

So this is sponsored by thtx. All it's doing is raising awareness of nafld in hiv and recommend doctors test of the disease. It isn't (and can't) link that message directly to Tesamorelin.

https://www.clinicaloptions.com/hiv/programs/2021/hiv-and-nash/clinicalthought/ct1/page-1#

jeffm34 wrote:

It's really not that difficult of a concept to understand but I will explain it again. They are treating the lipodystrophy which it is indicated for. One of the added benefits is that it will likely prevent NASH. There is absolutely nothing illegal about doing that. It's not even off label use which they could do anyways if they chose to.

SPCEO1 wrote: Actually, it is illegal for them to sell Egrifta that way (in a manner it is not approved for). So, while what you are saying is something they no doubt wish they could do (and the patietn would indeed benefit), they can only do so obtusely and that tends not to be very effective.

jeffm34 wrote: If THTX can't convince physicians to prescribe egrifta now to treat and prevent NASH in their HIV patients. (which they could be doing) why would you expect them to do any better in the general population?