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Therma Bright Inc V.THRM

Alternate Symbol(s):  TBRIF

Therma Bright Inc. is a Canada-based company, which is a developer and partner in a range of diagnostic and medical device technologies. It focuses on providing consumers and medical professionals with solutions that address medical and healthcare challenges. It is involved in developing, acquiring, manufacturing, and marketing proprietary healthcare and medical devices for the consumer and institutional marketplace. Its product offerings include Covid-19 diagnostic test product line, such as AcuVid COVID-19 Rapid Antigen Saliva Test and AcuVid COVID-19 Rapid Antibody Test; Sores & Bite Inflammation Therapy product line, such as InterceptCS Cold Sore Prevention System and TherOZap, and Muscle Pain & Blood Circulation Health Therapy product line, such as Venowave, which is a circulation booster designed to improve circulation in the lower extremities. Its products include Benepod, Inretio, AI4LYF, Invixa and Instatin, and others.


TSXV:THRM - Post by User

Post by Watchman21on Apr 15, 2022 10:56am
654 Views
Post# 34606378

My OPINION only - Why AcuVid will get FDA EUA

My OPINION only - Why AcuVid will get FDA EUA

In My OPINION….Here is why I believe AcuVid is assured to be granted FDA EUA

 

Clinical Studies

  • AcuVid US Clinical Study:
    • PPA 80.3% / NPA 98%. -    
    • US Sample Size: 230+ samples
  • AcuVid Brazilian Clinical Study:  (If FDA accepted Diasorin’s International results, so should they accept AcuVid’s international results)
    • PPA 85.7% / NPA 97.8%.  
    • Brazil Sample Size: 260_ Samples
  • AcuVid Blended Clincials:  -
    • PPA 83% / NPA. 97.9%. 
    • Total Sample Size:  490+ 

 

FDA EUA CLINICAL MINIMUMS

  • US FDA EUA Requirements:
    • PPA:  80.0% / NPA 95% Or Higher

 

Competition Clinicals Comparisons

  • Abbott’s Binax NOW COVID 19 AG Test  (approved Dec 16, 2020) -
    • PPA 84.6% / NPA 98.5%. - (long before Delta, Omicron and BA-2 Omicron). 
    • US Sample Size. 460
  • Diasorin LIAISON SARS-CoV-2 Ag  (approve March 26, 2021)   - Combined US & European Clinical Results
    • PPA. 84.4% / NPA 99.5% (before Delta, Omicron and BA2 Stealth Omicron)
    • US & EUROPE sample Size:  399   ( 2 labs in US & 2 Labs in Europe)

 

Cross Reactivity Studies

  • Cross Reactivity Studies - Nasal- borne viruses & bacteria (like all the other antigen tests). 
  • ADDED Cross Reactivity Studies -  Mouth-borne viruses & bacteria

 

Alternative Rapid Testing Solutions Being Accepted for FDA EUA

  • NASAL TEST:  Detect (https://detect.com)….  - FDA EUA.  October 29, 2021. - PCR Test
  •  
  • Challenges  these electronic devices have - 
    • Limited Production Capabilities - no way any of these can produce 500K per week or service 500K people per week with only 100 units produced per month
    • Costly / Expensive Solutions - not affordable by the masses 
    • Distribution:  requires huge distribution to service 500K people per week
  • AcuVid benefits
    • Meets Standards:  Meets FDA EUA PPA and NPA results, cross reactivity tests & WHO Variants of Concern test standards
    • Affordable:  cost similar to other Covid-19 Rapid Antigen Nasal Test solutions
    • Production:  Meets the November 2021 Guidance for 500K tests per week 

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