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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by qwerty22on Aug 11, 2022 1:42pm
128 Views
Post# 34888905

RE:RE:Tranche 3 by end 2023

RE:RE:Tranche 3 by end 2023

It's a little odd the way Paul talked about a potential third product. The way I took it is he sees his sales force as having the ear of 2000 physicians and the third product might be somebody who wants to access those doctors. It just struck me as an odd way to word things. Presumably mostly HIV specialist  docs but maybe those dealing with co-morbidities in the hiv population. It's hard to find candidate drugs, most hiv related drugs (and hep c etc) are in the hands of big Pharma.


palinc2000 wrote: Why woukd they need to make an acquisition to meet the 90 million $ in revenue?You really think they would do a bad deal which would involve a cash outlay to get their hands on the 3 rd Tranche?These are the kind of statements which I consider as being the same as calling mgmt stupid..
If the water problem is resolved in October 2022 why do you think approval of F8 is a BIG IF?
FDA has approved the revised protocol for Phase 3 in Nash...Logic would dictate that FDA will accelerate the approval process for F 8......pure logic!!!
Again Spceo you seem to question or undercut a lot of statements on operational issues ....dont you have any confidence in their ability to run the business on the day to day basis?


 

SPCEO1 wrote: I have said that it seemed like a reach to get the F8 approved by the end of  in order to get the extra year of interest only payments on the Marathon loan and the extra year on the term of the loan. Yesterday Paul indicated they would file the F8 as soon as the water situation is cleared up which the FDA is still saying on their website will be by October. If that all holds up and there are no delays, they could have the F8 approval in hand by the end of 2023. Still a big "if", but certainly possible. 

TH also would need to get to $90 million in trailing year revenues, so that would likely require an acquisition of some sort between now and then of revenues. The risk is they do a bad deal to acquire revenues just to be sure they meet that goal and are able to take down tranche 3 and trigger the benefits of doing it a bit early. 

Of course, if they end up with three 25 member cohorts in the phase 1b and half of the patients in those cohorts see nice benefits from TH-1902, then all of the loan related things may become irrelevant since raising new equity on attractive terms as well as partnership capital would likely become a more preferred route to raise money. With a phase 2 trial likely requiring $40 million or more (can't see how they could get a registrational phase 2 trial done near the low end of Paul's cost estimate) they will need capital. Since the brokers know that, they would likely start recommending TH's stock soon as good cancer data is available in order to have a chance to be involved in any potential capital raise.

Now they could pull down the remaining amounts on the Marathon loan and raise less equity. And they could renegotiate the Marathon loan to up the amount they could borrow to finance a phase 2, but that seems unlikely unless they (and especially Marathon) were really very, very confident about the outcome of the phase 2 trial. If you knew you had a huge winner on your hands, debt financing would be ideal for shareholders. But you need to get that call right. 




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