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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by PWIB123on Oct 26, 2022 3:24pm
71 Views
Post# 35051006

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:News out 👀

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:News out 👀Appreciate the references qwerty22.  So, while timelines weren't met initially and the trial has seemed slow, maybe THTX is not that far out of line with what is normal.  Someone earlier mentioned that we are 20 months into the Ph.1.  I wasn't sure if Ph.1 a is considered a separate timeline from Ph.1b, when considering a 3 month to 1 year timeframe for completion, or if they are combined.  I assumed they are two separate timelines.  

qwerty22 wrote: Bicycle started their lead Ph1 with BT5528 in Nov 2019.
https://investors.bicycletherapeutics.com/news-releases/news-release-details/bicycle-therapeutics-announces-first-patient-dosed-phase-iii

It took them until Oct 2021 to give a readout on the first 24 patients.
https://investors.bicycletherapeutics.com/news-releases/news-release-details/bicycle-therapeutics-announces-interim-bt5528-phase-i-clinical

By Sept 2022 they were still only reading out on 29 patients.
https://investors.bicycletherapeutics.com/news-releases/news-release-details/bicycle-therapeutics-announces-bt5528-phase-i-dose-escalation

IDK if Bicycle and Sutro are just as slow as THTX but they all look to be on similar timelines. Looks to me like some of Bicycle's important readouts happened  2-3 years after the start of Ph 1.


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