TSXV:BTI.H - Post by User
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Comonreally42on Nov 25, 2022 1:24am
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Post# 35127374
Ossianix
OssianixOssianix, an antibody engineering company, today announced the results of a non-human primate study demonstrating best-in-class blood-brain barrier (BBB) delivery by single domain antibodies. The Ossianix proprietary VNAR shuttle TXP1 showed efficient transfer into all six regions of the brain examined, with the hippocampus showing an over 30-fold increase in levels of the molecule compared to the control. The TXP1 shuttle was administered at a dose of 1.35 mg/kg by intravenous injection and reached a concentration of 4 nM in the brain after 20 hours.