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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by SPCEO1on Dec 02, 2022 3:36pm
209 Views
Post# 35147450

RE:RE:RE:RE:RE:Not surprising

RE:RE:RE:RE:RE:Not surprisingI think one can safely say they made this change because they were not getting the results required to move forward. If they kept going, they would be wasting our money. So, they made the sensible call to try another approach to see if they can find the results they originally expected.   

JayjayUSA12007 wrote: Quote:"If they aren't being 'forced' to stop this by safety then I see no great harm in running this another few months to see what the full cohort tells you. It just sounds like a big decision to stop the trial and a relative small reason and solution. "

I disagree with this assessment. We always know that Thera management is very, very conservative and risk adverse. IMO, I think they made this move to err on the safe side.
The amended trial protocol likely will try to take into account existing data gathered in Phase 1a/b which will save time and efforts.


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