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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by scarlet1967on Jan 03, 2023 6:57pm
168 Views
Post# 35201769

RE:RE:Another biotech in Nash

RE:RE:Another biotech in Nash

“While the biotech studied the drug in NASH “as a model disease” in context of fibrosis and inflammation, the chief executive noted that running NASH trials, especially pivotal ones, can get very costly. “We’d love to be able to get back to it, but from an economics viewpoint, financial viewpoint, it’s sort of let’s go for the orphan diseases first,” Pfost added, noting a possibility of a future partnership to tackle the disease.”

 

Fibrosis startup touts mid-stage NASH trial as it moves sole candidate forward – Endpoints News

 

https://seekingalpha.com/pr/19069005-chemomab-reports-top-line-results-from-cmminus-101-phase-2a-liver-fibrosis-biomarker-trial-in

 

Based on the price action it seems like some investors were disappointed due to the fact the trial is “parked”!

In terms of science the results from their phase 2 trial were from only 23 patients confirming safety and reduction of fibrosis based on FibroScan and levels of bio markers, I can’t find anything about the NAS score either. 

THTX’s NASH asset is far more valuable than this tiny trial and in my opinion although some analysts have priced in both NASH and oncology in their reports the market hasn’t!! Again their NASH and oncology assets are not worthless unless they throw away the entire sort1 project and NASH, so far they haven’t but investors are not convinced, an issue which has to be addressed.

 

 

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