RE:RE:RE:RE:RE:RE:Very encouraging, but approval will take timeI don't think they mentioned the path to approval is SD even so having extended period of stable disease among heavily treated patients is impressive. The eye toxicity seems to be manageable by prophylactics the nerv issue based on Dr. Merci's past experience and as per Christian's comments(pre clinical observations) is supposed to be dealt with based on lower and more frequently dosing this time also based on body weight rather than surface maybe because cancer patients loose weight because of cancer itself and treatments so they can get that tolerable dose more confidently and accurately?!
Again a lot of info during a rather short time, they could do with a longer call in my opinion rather than rushing through questions. Nothing about the timing, funding and very little about partnership if any. My impression is they are hopeful/more positive about getting efficacy but worried about toxicity issues as it seems the new design has bits added to it to deal with the issue..,