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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Sep 18, 2024 12:53pm
60 Views
Post# 36229260

RE:RE:RE:How does Accelerated Approval work

RE:RE:RE:How does Accelerated Approval work The accelerated approval program may lower the operational hurdles for launching the above-mentioned products by allowing studies with surrogate endpoints to be reviewed for early approval, in which the sample size is smaller and the results are available more expeditiously than studies with true endpoints,” wrote Satoshi Kato and Shunsuke Ono, of the laboratory of pharmaceutical regulatory science at The University of Tokyo.

"Accelerated approval products were also often given other regulatory designations such as orphan drug (67%), priority review (55%), breakthrough therapy (36%), and fast track designations. Products that were deemed to have an acceptable benefit-risk profile were more likely to have another regulatory designation (89%) compared to products with a favorable benefit-risk profile (73%)", the researhcers wrote.

ONCY's pelareorep has orphan drug and fast=track designation.
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