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Bullboard - Stock Discussion Forum
Boundless Bio Inc
BOLD
Healthcare
Biotechnology
Boundless Bio, Inc. is a clinical-stage oncology company, which is engaged in cancer therapeutics that addresses the unmet need in patients with oncogene amplified tumors by targeting extrachromosomal DNA (ecDNA). Using its proprietary Spyglass platform, it identifies targets essential for ecDNA functionality in oncogene amplified cancer cells, then designs and develops small molecule drugs...
called ecDNA-directed therapeutic candidates (ecDTx) to inhibit those targets. Its lead ecDTx, BBI-355, is an oral, selective inhibitor of checkpoint kinase 1 (CHK1), which manages ecDNA replication and transcription in cancer cells. BBI-355 demonstrated CHK1 inhibition and tumor regressions in ecDNA-enabled preclinical cancer models and is being studied in a first-in-human, Phase I/II clinical trial in patients with oncogene amplified cancers. Its second ecDTx, BBI-825, is an oral, selective inhibitor of ribonucleotide reductase, which is essential for ecDNA assembly and repair in cancer cells.
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Bullboard (NDAQ:BOLD)
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whytestocks
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Post by
whytestocks
on Sep 11, 2024 8:03pm
Boundless Bio to Participate in the 2024 Cantor Gl
NEWS: $BOLD Boundless Bio to Participate in the 2024 Cantor Global Healthcare ConferenceSAN DIEGO, Sept. 11, 2024 (GLOBE NEWSWIRE) -- Boundless Bio (Nasdaq: BOLD), a clinical-stage
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whytestocks
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Post by
whytestocks
on Apr 11, 2024 9:45pm
Boundless Bio Announces First Patient Dosed in First-in-Huma
Just In: $BOLD Boundless Bio Announces First Patient Dosed in First-in-Human Phase 1/2 Clinical Trial of BBI-825 in Cancer Patients with Resistance Gene AmplificationsSTARMAP ( S tudy T reating A
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