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Bullboard - Stock Discussion Forum Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and... see more

TSX:ONC - Post Discussion

Oncolytics Biotech Inc > PR more partial responses form Adlay trial...
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Post by CarbonWarrior on Nov 21, 2022 1:44pm

PR more partial responses form Adlay trial...

Wow, there are now more are PR now. Insane that market is not reacting.... to cure for cancer

s of the abstract's data cut-off date (June 2, 2022), ten patients had been treated in the trial, with four achieving a partial response (two confirmed, two unconfirmed) and five showing stable disease (SD). Eight of the nine patients achieving a partial response (PR) or SD remained on study and continued to receive treatment as of the cut-off date. Updated and additional data from the trial will be presented in the poster corresponding to the abstract in accordance with the SABCS embargo policies.
Comment by Noteable on Nov 21, 2022 2:09pm
These results have further added to ONCY's IND-213 two-arm study results which demonstrated that pelareorep is effective when added to the chemotherapy agent paciltaxel (and without the need for any other I/O agent) versus paclitaxel alone. - and that the addition of pelareprep was responsible for the partial and stable disease responses seen. Any global regulatory ...more  
Comment by Noteable on Nov 21, 2022 4:41pm
From the SABC submitted abstract ... Among the 10 treated patients, 2 (20%) patients achieved confirmed partial response (PR), 2 (20%) patients achieved unconfirmed PR, and 5 (50%) patients showed stable disease (SD). One patient in DL1 group achieved a confirmed PR and later progressed, and the other 8 patients who had PR or SD continue to receive treatment as of the data cut.
Comment by Noteable on Nov 21, 2022 4:49pm
By the data cutoff date of June 2nd, 2022, a total of 10 female patients were enrolled, with a median age of 58 years (range 36-67). Two (20%) patients had failed more than one prior line of endocrine therapy for advanced/metastatic disease, and 3 (30%) patients were previously treated with a CDK4/6 inhibitor.  8 /10 patients who had PR or SD continue to receive treatment as of the data ...more  
Comment by CarbonWarrior on Nov 21, 2022 4:52pm
The one patient that got PR than progressed was going to not recover anyway, that patient was a lost cause... His life got extended nonetheless but we will never be able to measure it.  The rest (89%) got their life extended for sure (either by SD or PR)... As they live on and on, this baby should grow. Not sure why this company is not releasing a more aggressive news release... Such as... ...more  
Comment by Noteable on Nov 21, 2022 5:08pm
Since there has been no clinical trial assessing AN1004 in Chinese population, the Adlai Nortye bridging study (REO 026-1) was initiated to evaluate its safety and tolerability in combination with PTX in Chinese patients with HR+/HER2- advanced/metastatic breast cancer. The conclusion of the study was that: To date (June 2, 2022), intravenous administration of AN1004 plus PTX was demonstrated to ...more  
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