Theratechnologies Inc T.TH

Bladder cancer study

[jeffm34]

https://www.docwirenews.com/gu-oncology-now/diagnostic-and-therapeutic-implications-of-sortilin-expressed-on-the-surface-of-bladder-carcinoma-cells/amp/

[Wino115]

Very interesting find - thanks for sharing.  There's a lot of pertinent info.  We've been discussing this aspect and they reiterate what we had already understood to be the case on normal vs. cancer cells. "Previously, it has been reported that only 10% of total sortilin could translocate to the surface of normal cells while 90% remained in cytoplasmic organelles such as

[SPCEO1]

Thanks for reading that and pulling out the salient points for us. The new info here is that while the sortilin receptors are overexpressed on the surface in cancer cells, the interactions between TH-1902 and different types of cancer cells likely varies. That will make cracking the code of each type of cancer more difficult than if all cancer cells reacted similarly. But TH has the lead in this