Thiogenesis Therapeutics Corp TTIPF

Primary Symbol: V.TTI

Healthcare Biotechnology

Thiogenesis Therapeutics, Corp. is a Canada-based clinical-stage biopharmaceutical company. The Company is developing sulfur-containing prodrugs that act as precursors with the potential to treat serious pediatric diseases with unmet medical needs. The Company’s lead compound, TTI-0102, is a disulfide, made up of two thiols that lead to two independent cysteamine molecules. Cysteamine is a thiol that has been rigorously studied and tested. It is the active ingredient used in drugs to treat the lysosomal storage disease - (nephropathic) cystinosis. TTI-0102 has been developed to address the obstacles facing thiol-based drugs, their short half-life, gastrointestinal (GI) side effects and dosing limitations. As a prodrug, TTI-0102 is metabolized into cysteamine molecules after it is ingested. The metabolic process acts as a gating mechanism. TTI-0102’s initial applications are for MELAS, Leigh syndrome, Rett syndrome and pediatric non-alcoholic steatohepatitis (NASH).

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Thiogenesis Therapeutics Corp

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Post by SkywalkerofLukeon Jan 02, 2025 5:48pm

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Post# 36385309

Good Recap on Thiogenesis

Good recap of Thiogenesis Therapeutics Corp. (TTI.v TTIPF) and the development of the drug TTI-0102 which is designed to treat pediatric NASH by releasing cysteamine, a potent antioxidant that can reduce oxidative stress and inflammation.

More on Thiogenesis and the addressable market in the post: https://www.reddit.com/r/CanadianStockExchange/comments/1hs6occ/thiogenesis_therapeutics_corp_ttiv_ttipf/

*Posted on behalf of Thiogenesis Therapeutics Corp.

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