Agilent Technologies Inc. (NYSE: A) today introduced the GenetiSure
Pre-Screen Kit, a high-throughput oligonucleotide microarray for
screening aneuploidy and other genomic aberrations in the 5- to 10-Mb
range from single cells in three- and five-day embryos.
Agilent’s kit allows for a turnaround time of less than eight hours from
DNA extraction to data analysis—an industry first. The kit consists of a
microarray that can run up to 14 samples and two reference samples
simultaneously, so more embryos can be screened without significantly
increasing costs.
“No other array platform currently has this high-throughput capacity,
with less than eight hours turn-around time, with this resolution,” said
Dr. Richard Choy, Ph.D., director of the Pre-Implantation Genetic
Diagnosis Center and associate professor of the Department of Obstetrics
and Gynecology at the Chinese University of Hong Kong.
“We are cautious about the overall cost and value of our screening,”
Choy said. “We are able to use the capacity of Agilent’s kit to address
this price sensitivity, and it will be key technology in our work.”
Agilent’s GenetiSure prescreen kit was developed based on a protocol
designed by Ali Hellani, Ph.D., director of the Viafet Genomic Center in
Dubai.
“Agilent’s microarray data can show small, few-megabase microdeletions
that are very difficult to detect at a single-cell level,” Hellani said.
The GenetiSure Pre-Screen array is based on Agilent’s market-leading
technology for high-resolution oligonucleotide comparative genomic
hybridization. The kit contains all necessary reagents to enable
whole-genome amplification and labeling of single cells. The microarray
is compatible with Agilent’s CytoGenomics software (version 3.0 or
higher) for easy data analysis.
To learn more about the GenetiSure Pre-Screen Kit, visit www.agilent.com/genomics/genetisure/prescreen.
Agilent’s GenetiSure Pre-Screen Kit is for research use only, not for
use in diagnostic procedures.
About Agilent Technologies
Agilent Technologies Inc. (NYSE: A), a global leader in life sciences,
diagnostics and applied chemical markets, is the premier laboratory
partner for a better world. Agilent works with customers in more than
100 countries, providing instruments, software, services and consumables
for the entire laboratory workflow. Agilent generated revenues of $4.0
billion in fiscal 2014. The company employs about 12,000 people
worldwide. Information about Agilent is available at www.agilent.com.
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Copyright Business Wire 2015