VANCOUVER, British Columbia, Aug. 02, 2018 (GLOBE NEWSWIRE) -- Breathtec Biomedical Inc. (CSE: BTH)
(CNSX: BTH) (FRANKFURT: BTI) (OTCQB: BTHCF) (the “Company”) is pleased to announce that it will be opening a
new drug development division and has signed a Letter of Intent (“LOI”) to acquire 100% of the shares of Nash Pharmaceuticals Inc.
(“Nash Pharma”). Nash Pharma is a clinical stage pharmaceutical development company focused on drug repurposing in the areas of
non-alcoholic steatohepatitis (NASH), chronic kidney disease (CKD) and inflammatory bowel disease (IBD). Through its ongoing
research programs, Nash Pharma has developed data that supports the advancement of up to 7 drug candidates into phase II trials.
Pursuant to the LOI, the Company will enter into a definitive agreement whereby the Company, prior to the
closing of the transaction, will complete a consolidation of its securities on a 2-to-1 basis. This will result in the
Company having 28,682,012 common shares, 6,005,833 outstanding warrants and 2,147,500 outstanding options. Further, the
Company will acquire all of the issued and outstanding common shares of Nash Pharma in consideration for the issuance by the
Company of 15,800,000 common shares of the Company and will issue an additional 14,800,000 warrants at a price equal to the
exercise price of the Nash Pharma warrants.
Concurrent with the transaction, the Company anticipates that it will complete a private placement financing of
its securities to arm’s length parties for aggregate gross proceeds of up to CDN$1,000,000, at a price per security to be
determined based on the context of the market, with such proceeds to be allocated towards funding development of the business
division of Nash Pharma.
The Company is committed to and will continue to advance the research and development program for its FAIMS
technology and will be providing an update to the market on its progress shortly.
About Nash Pharmaceuticals Inc.
Nash Pharma is a Canadian based, privately held drug development company focusing on developing repurposed
therapeutic drugs. Drug repurposing (also known as re-profiling, re-tasking or therapeutic switching) is the application
of approved drugs and compounds to treat a different disease than what it originally developed for. Nash Pharma’s
business model seeks to minimize investment and drug development risk by taking advantage of regulatory approved drugs and
discovering alternative clinical uses by accelerating entry into phase II clinical trials (humans).
The benefit of this approach to drug development is that if promising data is generated
from early animal model research, the drug can often be moved immediately into phase II studies without having the costs and
risks associated with preclinical work. The preclinical work phase is the highest risk phase of drug development and can
take up to 8 years to complete. A phase II study provides the greatest opportunity for significant value creation for a drug
development company.
Nash Pharma, under the scientific and research leadership of Dr. Mark Williams, PhD MBA has been focusing its
research on the following three areas:
- Non–Alcoholic Steatohepatitis (“NASH”)
NASH is a serious condition in which fat accumulates in liver tissue in people who consume little or no
alcohol. It is the most severe form of non-alcoholic fatty liver disease (“NAFLD”), which in some individuals can progress to
fibrosis (scarring) and ultimately hepatocellular carcinoma (liver cancer).
Market Opportunity
According to a new report published by Allied Market Research, “Global Opportunity Analysis and Industry
Forecast, 20212025," the global NASH market was valued at $1.17 Billion in 2017, and is expected to reach $21.4 Billion by 2025,
growing at a CAGR of 58.4% from 2021 to 2025.
Nash Pharma Technology
Nash Pharma has identified up to two potential compounds, which statistically significantly reduced the NAFLD
score in an industry standard animal model of NASH by at least 2 points.
- Chronic Kidney Disease (“CKD”)
CKD is a condition in which the kidneys are damaged or cannot filter blood as well as healthy kidneys, often as
a result of fibrosis. Because of this, excess fluid and waste from the blood remain in the body and may cause other health
problems. 30 million people or 15% of US adults are estimated to have CKD.
Market Opportunity
The global market for CKD drugs continues to proliferate at a significant pace, driven by the increasing number
of CKD patients and the growing need of novel treatments to improve patients’ quality of life. The global CKD drug market
stood at US$11.5 Billion in 2015. Burgeoning at a CAGR of 3.60% between 2016 and 2024, the market’s opportunity is expected to
reach US$15.8 Billion by the end of 2024.
Nash Pharma Technology
Nash Pharma has identified up to three drug candidates that when tested in an industry standard mouse model of
kidney fibrosis, statistically significantly reduced fibrosis scores to equivalent levels to Telmisartan, a known anti-fibrotic
compound.
- Inflammatory Bowel Disease (IBD)
Inflammatory bowel disease (IBD) is an umbrella term used to describe disorders that involve chronic inflammation of the
digestive tract. This condition causes long-lasting inflammation and sores (ulcers) in the innermost lining of the large intestine
(colon) and rectum.
Market Opportunity
The global IBD treatment market is valued at US$10.52 Billion in 2016. Rising at a steady 2.6% CAGR between 2017 and
2025, the market is likely to be valued at US$14.8 Billion by the end of 2025. In 2016, North America led the
global IBD market, which is attributable to the rising incidence of the disease witnessed among men and women alike in the region.
The incidence of ulcerative colitis and crohn's disease is high in US and Canada, which fuels the demand for IBD treatment
in North America.
Nash Pharma Technology
Nash Pharma has identified two potential compounds that statistically significantly improved multiple disease
related endpoints in an ulcerative colitis model compared to untreated animals. Both candidates appeared as effective as the known
approved front-line therapy, 5-amino salicylic acid (5-ASA) in reducing disease severity.
For more information please visit: www.nashpharmaceuticals.com
ABOUT BREATHTEC BIOMEDICAL INC.
Breathtec Biomedical, Inc. (“Breathtec”) was formed to propel innovative research in the area of airborne
analysis as a medical screening tool. Our efforts are aimed at leading the development of commercially viable methods for the early
screening of certain pathogens. Our primary avenue of investigation is focused on innovation and advances in the field of
specialized mass spectrometry. For more information, visit www.breathtecbiomedical.com.
CONTACT INFORMATION
Christopher J. Moreau
CEO
Breathtec BioMedical Inc.
604.398.4175 ext 701
info@breathtechbiomedical.com
investors@breathtecbiomedical.com
www.breathtecbiomedical.com
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adequacy or accuracy of the content of this news release. This news release contains forward-looking statements relating to product
development, licensing, commercialization and regulatory compliance issues and other statements that are not historical facts.
Forward-looking statements are often identified by terms such as “will”, “may”, “should”, “anticipate”, “expects” and similar
expressions. All statements other than statements of historical fact, included in this release are forward-looking statements that
involve risks and uncertainties. There can be no assurance that such statements will prove to be accurate and actual results and
future events could differ materially from those anticipated in such statements. Important factors that could cause actual results
to differ materially from the Company’s expectations include the failure to satisfy the conditions of the relevant securities
exchange(s) and other risks detailed from time to time in the filings made by the Company with securities regulations. The reader
is cautioned that assumptions used in the preparation of any forward-looking information may prove to be incorrect. Events or
circumstances may cause actual results to differ materially from those predicted, as a result of numerous known and unknown risks,
uncertainties, and other factors, many of which are beyond the control of the Company. The reader is cautioned not to place undue
reliance on any forward-looking information. Such information, although considered reasonable by management at the time of
preparation, may prove to be incorrect and actual results may differ materially from those anticipated. Forward-looking statements
contained in this news release are expressly qualified by this cautionary statement. The forward-looking statements contained in
this news release are made as of the date of this news release and the Company will update or revise publicly any of the included
forward-looking statements as expressly required by applicable law.
