Catabasis Pharmaceuticals and Parent Project Muscular Dystrophy to Host a Webinar on PolarisDMD: Phase 3
Clinical Trial of Edasalonexent (CAT-1004) in Duchenne Muscular Dystrophy
Webinar at 1:00pm ET on November 7
Catabasis Pharmaceuticals, Inc. (NASDAQ:CATB), a clinical-stage biopharmaceutical company, and Parent Project Muscular
Dystrophy (PPMD) will host a webinar: “PolarisDMD: Phase 3 Clinical Trial of Edasalonexent, a Novel NF-kB Inhibitor, in Duchenne
Muscular Dystrophy,” on Wednesday, November 7, 2018 at 1:00pm ET.
Speakers Include:
Joanne Donovan, M.D., Ph.D., Chief Medical Officer, Catabasis Pharmaceuticals
Pat Furlong, Founding President and Chief Executive Officer, Parent Project Muscular Dystrophy
Dr. Donovan will discuss the Phase 3 PolarisDMD clinical trial studying edasalonexent in Duchenne muscular dystrophy (DMD),
which is enrolling boys ages 4 to 7 (up to 8th birthday) regardless of mutation type who have not been on steroids for
at least 6 months. Topics will include discussion of the PolarisDMD clinical trial, endpoints, inclusion and exclusion criteria,
and information on edasalonexent, including previous clinical results that showed preserved muscle function in boys affected by
Duchenne with edasalonexent treatment compared to the off-treatment period as well as significantly improved biomarkers.
The webinar can be accessed by visiting
http://bit.ly/2Puskwr.
About Edasalonexent
Edasalonexent (CAT-1004) is an investigational oral small molecule that is being developed as a potential new standard of care for
all patients affected by DMD, regardless of their underlying mutation. Edasalonexent inhibits NF-kB, which is a key link between
loss of dystrophin and disease progression. NF-kB has a fundamental role in skeletal and cardiac muscle disease in DMD. Catabasis
is currently enrolling the single global Phase 3 PolarisDMD trial to evaluate the efficacy and safety of edasalonexent for
registration purposes. In the clinic, we observed that edasalonexent preserved muscle function and substantially slowed disease
progression compared to rates of change in a control period, and significantly improved biomarkers. Edasalonexent continues to be
dosed in an open-label extension of the MoveDMD Phase 2 clinical trial. The FDA has granted orphan drug, fast track, and rare
pediatric disease designations and the European Commission has granted orphan medicinal product designation to edasalonexent for
the treatment of DMD. For a summary of clinical results, please visit
www.catabasis.com.
About Catabasis
At Catabasis Pharmaceuticals, our mission is to bring hope and life-changing therapies to patients and their families. Our lead
program is edasalonexent, an NF-kB inhibitor in development for the treatment of Duchenne muscular dystrophy. The global Phase 3
PolarisDMD trial is currently enrolling boys affected by Duchenne. For more information on edasalonexent and our Phase 3 trial,
please visit
www.catabasis.com.
Investor and Media Contact
Catabasis Pharmaceuticals, Inc.
Andrea Matthews, 617-349-1971
amatthews@catabasis.com
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