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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Post by MrMugsyon Nov 02, 2022 9:25am
320 Views
Post# 35065780

There we are ...

There we are ...Finally - 6 months to the day ... roughly 180 days to close.
The CITA back-up plan is no more.
The final hurdle to co-listing is the price and don't look for anything short-term.
Won't be going until we're heading towards ~$6/share.

So ... just understand the stage is set.

-------------------------

Now - looking at the financials for Nov 14 - Nov 18.
Hoping for a more thorough update w.r.t IBD and the direction they are going with it.
IBD has been pushed out a few times and they are being hush-hush as to why.
I would assume 352 to be shelved (for now) as 346/IBD will be the focus and just maybe 352 becomes redundant with the improved 346 formulation.

346 Acute plan and figuring out the shortest path to 346 Chronic (P2 Confirmatory) will be top-of-mind in 2023.  IMO. 

Schmoozing Institutional Investors in 2023 is likely the key business initiative (now that CITA has been erased from any future plans - pure play drug developer).

-------------------------

Just wish we really understood what "significant dose reduction" meant and how it affects Acute and Chronic drug development.  Acute is easy to understand but how the dose reduction affects a Chronic plan is anyone's guess.  More of a 2023 thing anyway.

One step at a time. 

Good Luck !
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