RE:RE:RE:RE:Up until now I didn't know what TCID meantLOL Maybe U should give it a rest with your misinformation campaign
Trying to give SONA a better LOD when in the news release its LOD is 210
As for classifying Covid case its all a name Asymptomatic , Symtomatic, PRe-sym.
What matters is the LOD and the Viral load which is the same Viral load across all classification ASy, Sym , Pr-sym.
RE:Up until now I didn't know what TCID meant
Sure I will do that... Some say we have 210 and others 105. I would agree 210 divided by the 50 = 105. The shorts are hitting trying to twist things, and miscontrue so weak hand sell... Hold the approvals are coming... I'll tweet the Dr.
shoosh22 wrote: whatdoiknow123 wrote: TheeRook wrote: This is probably beyond your understanding but here i Link again.
Sona's limit of detection (LOD) of 2.1 by 10^2 TCID50 = 210 2.1 x 100 = 210
10^2 = 100 = 10 x10
10^3 =1000 = 10 x 10 x 10
10^ 4 = 10000 = 19 x 10 x 10 x 10
and on and on
its called Scientific notation
Best-in-class assays demonstrate a limit of detection (LoD) of ~100 copies of viral RNA per milliliter of transport media. However, LoDs of currently approved assays vary over 10,000-fold. Assays with higher LoDs will miss more infected patients, resulting in more false negatives. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302192/ oxinos wrote: After repeatedly searching on google I finally found what the TCID stands for:"Tissue Culture Infective Doses" . If any of you have a twitter account could you please ask Dr. Michael Mina to explain what the load of detection 2.1x10^2 TCID 50 means? This explanation may go a long way in dispelling all the naysayers regarding the accuracy of Sona's lateral flow antigen test.
THEE ROOK,
your numbers are correct but if you had been following the recent articles, expert opinion and in-depth analysis you would have seen (or perhaps you have but prefer to ignore) that the experts are beginning to think that the extremely sensitive tests ie. PCR lab tests operating with high number of ct cycles are actually counter-productive, often picking up irrelevant levels of virus and even remnant genetic fragments left behind after the patient has recovered. This leads to non-contagious patients being picked up and delaying the really important thing which is picking up early-phase and Asymptomatic patients. Medicine is not Mathematics, Patients are not Calculators, it is looking as if the rather less sensitive tests may actually be the best ie. Antigen Tests.
Dr Michael Mina, Harvard Public Health, said it may be better to test more often with less sensitive tests than relying on the PCR lab tests which can pick up unwanted readings. That is not the case with Sona's Antigen test testing Asymptomatic people. The way you throw things out there.. you always have to pick on sona for some reason.. Give it a rest.