Sona Nanotech Inc C.SONA

This is why SONA is different

[Findingmoney]

From the SONA site
Gold nanorods (GNRs) are small particles whose surface plasmon resonance (SPR) frequencies can be altered as a function of the length and width, giving these anisotropic particles optical properties useful in a host of applications (1,2). GNRs have been used in a number of biomedical applications, including as contrast agents for optical biomedical imaging and for their hyperthermal effects. One of the major barriers in the application of GNR-based materials, especially for in-vivo applications such as hyperthermal cancer treatment, is the efficient exchange and removal of cetyltrimethylammonium bromide (CTAB), the surfactant used exclusively in the large scale synthesis of GNRs. CTAB is a cytotoxic, cationic surfactant with an extremely low critical micelle concentration (3-5). Its function in the synthesis of the gold nanorods is still a matter of debate, but it is generally thought that the CTAB forms a strongly adsorbed bilayer around the surface of the growing gold particle (6-8).

The concentration of CTAB that is most often used in the synthesis of gold nanorods is 0.10 M or 100 times its critical micelle concentration, meaning a significant amount of CTAB remains in the bulk of the solution after the GNRs are made, which serves to stabilize the GNRs (prevents them from selfaggregating in solution)(6). The CTAB surfactant, so critical for GNR synthesis, is a significant impediment to in-vivo applications. A number of methods have been used to “remove” or partially exchange the CTAB including frequent solvent washing, treatments with surface active materials such as PEGylated thiols or other polymers (9-11). However, during surface exchange CTAB-coated GNR dispersions are destabilized, which results in particle aggregation and low recovery yields of GNRs. In addition, these surface modified GNRs are often contaminated with residual CTAB (9).

[teaboy1]

The gold nanorods have really made a big difference in sonas  high sensitivity. BUT remember it's not the only way to make a test more accurate.  The antibody (or antibody replacement like an Aptamer or affimer) is part of the test too.  for example - think of a car. The nanorods could be likened to the tyres/engine. Having the best possible tyres/engine will make a

[hieveverybody]

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[teaboy1]

But there are other sensitive solutions that are not antibodies also. For example the native antigen antibodies don't differentiate between SARS Cov1 and sars cov 2 ...  some of the other solutions like affimers and aptamers are really good replacements for antibodies as they are smaller and more specific with a high affinity.

[whatdoiknow123]

the differentiation is not at all relevant in respect of an ANTIGEN TEST for MASS SCREENING so no need to confuse the issue. You might not want crossover if you were looking  for Antibodies in the patients blood at a later date so see who had been infected by what in the PAST but that has NO RELEVANCE WHATSOVER to what the SONA ANTIGEN TEST is doing otherwise where ro you think they get their