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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Jun 05, 2023 9:27am
131 Views
Post# 35480112

RE:RE:RE:ONCY's pelareorep is now Phase 3-ready

RE:RE:RE:ONCY's pelareorep is now Phase 3-readyDr. Piccart also commented on pelareorep + paclitaxel's combination scoring high on the ESMO - Magnitude of Clinical Benefit Scale.

https://www.esmo.org/guidelines/esmo-mcbs/about-the-esmo-mcbs

ESMO-MCBS was developed in 2015 as a validated and reproducible scale that is applicable across the full range of solid tumours and since 2023 in hematological malignancies. The latter has been developed in collaboration with the European Haematological Association (EHA).

It incorporates a structured, rational and valid approach to clinical trial data interpretation and analysis that reduces the tendency to have judgements affected by bias or uninformed and/or idiosyncratic data interpretation that has been developed in accordance with the ethical framework for fair decision-making and public policy standard of “accountability for reasonableness

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