ATB-346 for Ulcerative Colitis?All longs, sorry been swaped with work, will pop in from time to time to drop my 2 cents
For diseases like Ulcerative Colitis, where ulcers in the large intestine are the core problem of the disease, the mucosal healing properties of the H2S pipeline are extremely exciting (this is why Phase 2a results are just simply incredible).
If you are able to reduce the inflammatory burden (NSAID component) and the hydrogen sulfide mediators confer additional mucosal protection (or healing), then 100% you have a very safe and likely to be well-tolerated treatment for Ulcerative Colitis.
These diseases require immunosuppressives so if there were a non-immunosuppressive way to treat patients with mild to moderate disease, you would effectively change the paradigm of treatment. No patient wants to be on immunosuppressives. Generally NSAIDs are not used in Ulcerative Colitis or Crohn's for pain because it causes ulcers. If ATB-346 heals the gastric mucosa for upper GI tract pathology could those same effects health the lower GI tract? McWhirter has no idea what he's talking about when he speaks about "coating the stomach", it's not bismuth (pepto bismol), Otena does not provide topical healing, otherwise, ATB-346 supporitories and enemas for Ulcerative Colitis right away! So if the effect is not topical, ATB-346 reduces systemic inflammation (NSAID) with massive GI (upper and lower GI tract) mucosal healing properties and is a non-immunosuppressive treatment in a 100% immunosuppressive world. So there's your strategy to penetrate the market.
Once amalgamation with Antibe Holding is complete, the first pop is market cap of combined entity. This will be very interesting to see what happens. Dan and co. (Echelon) better not screw this up with funny stuff, personally Dan should already be replaced imho, since he can't be trusted ever again to represent the interests of all shareholders. He screwed shareholders in June by misleading shareholders to sell low. Antibe is 100% manipulated and intentionally kept low to keep upside in their control. However after watching this from almost IPO until now, the SP does not make any sense and its going to blow very soon.
Get in while you can because it's only going up and buyers are coming!
GLTA!