Spectral Medical Inc T.EDT

Successful Covid Recovery from PMX treatment...

[mercedesman]

...using Polymyxin-B or PMX-DHP


Internal Medicine 2020 August 29

https://read.qxmd.com/read/32863364/successful-recovery-from-covid-19-associated-acute-respiratory-failure-with-polymyxin-b-immobilized-fiber-column-direct-hemoperfusion

"An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use of PMX-DHP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung."

MM


PS  a singel case, but if proven to be generally successful, I wonder what this might do to the estimated "addressable Market" of $ 1.5 B USD for Severe Sepsis alone (no-Covid times)? ...

Especially now that the world has tallied 30 million Covid cases and 930,000 deaths so far i less than one year (with about 3% mortality)...with no signs of abatement.

I'm thinking it might increase it !

MM

[mercedesman]

If the addressable market is doubled by Covid and one takes the mid point of the market penetrations (from teh Sept Presentation) , one ends up with an EBITDA target of $ 246 M  ($ 123M  x 2) Taking this EBITDA and converting to CAD $ 325 M  CAD$ EBITDA Taking an ultra conservative (?)  10 X multiple, one arrives at  $ 3.250 B Divided by # shares (say 300 M at that time

[hmmmmmmmm]

A solid find. A few highlights below. "Immediately after completing two days of PMX-DHP, his temperature decreased, his serum C-reactive protein (CRP) level fell, and his respiratory failure did not progress further." An investigation of patients who required admission to an intensive-care unit with serious forms of COVID-19 showed that the mortality rate was 81.0% among

[Stocktree]

Daiam, PMX saves "stage 4" COVID-19 elderly patients, and we're the ones flatlining...