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Bullboard - Stock Discussion Forum Spectral Medical Inc T.EDT

Alternate Symbol(s):  EDTXF

Spectral develops devices for unmet medical needs. Sepsis occurs in 1.7M Americans/year causing 250K deaths, often caused by endotoxin. Our devices measure and remove endotoxin from the bloodstream. An FDA confirmatory trial is underway. Dialco, a Spectral sub, offers SAMI, a novel instrument for renal replacement, cleared by FDA. Dialco is seeking FDA approval for DIMI a unique home dialysis... see more

TSX:EDT - Post Discussion

Spectral Medical Inc > Ronco et al Aug 2022 seems to still be pro-PMX (golden hr)
View:
Post by mercedesman on Jan 30, 2023 3:24pm

Ronco et al Aug 2022 seems to still be pro-PMX (golden hr)

with Next steps confirming benefiot for Covid-19 patients as well.

Euphrates/Tigris/Eupahs 2/Eden/other meta-analyses all "synching up" ?

https://www.frontiersin.org/articles/10.3389/fneph.2022.847305/full


Conclusion

In conclusion, in our center, we performed endotoxin removal therapy using PMX-HP as a COVID-19-bedside strategy protocol for endotoxic shock after a prompt and appropriate timing and selection of patients after the first-hour bundle and in case of unresponsive endotoxic shock. We found that selected patients could have some advantages from this adjunct therapy. Further studies are needed to confirm this strategy in COVID-19 patients. In addition, our next step will be to test the flowchart in future trials to place a role in endotoxin activity assessment and consequently, early, extracorporeal endotoxin removal by Polymyxin B hemoperfusion in clinical practice.

Comment by daviking on Jan 30, 2023 3:36pm
MM, Despite your excellent findings on the use of PMX  in other countries, it is the USA where TIGRIS is being monitored. If they can't find 40 more 'patients' soon, there will be another cash call, imo. DELAY! DELAY! DELAY! For such a great sounding theranostic it is sure frustrating to watch my investment get diluted, again and again, and again. $10 was always a pipe dream and ...more  
Comment by mercedesman on Jan 30, 2023 4:36pm
DV While Tigris has not picked up significantly post-Covid (based on the last NR), as hoped, that does not mean one should extrapolate that there is 40 months to go. The FDA will focus mainly on Tigris/Euphrates for the reason you state (US only is the most important data), that does not mean that they will ignore other international RWE, Eden,growing Covid-19/PMX data, and a growing consensus ...more  
Comment by hmmmmmmmm on Jan 30, 2023 5:16pm
So many words to say so little McShill. We thought you were big on facts.. The fact is that at the most current rate reported by Spectral it WILL take 40 months to enroll 40 patients. At the rate we've seen over the last 6 months it will take closer to 20 months. Or at the rate since Tigris started- it's back to around 40 months.  Take your pick. (or just keep ignoring "facts ...more  
Comment by Bagelboy74 on Jan 30, 2023 5:40pm
Amen Hmmmmm, just checking on this lump again and I see MM is still spewing out the same garbage. I also see he or one of his diciples unloaded a wack of shares last week. Just hoping this dud hits 50 cents again so I can cash out. 
Comment by mercedesman on Jan 30, 2023 5:48pm
Hmmmm Disingenuous to imply the next 40 will be enrolled at the rate of one patient per month (or even two) - given the possiblity of 20 + sites, RSV & Covid waning etc.  I'm willing to see what happens Q1 and Q2 Didn't say stoppage at 90 was a given.  Only VERY possible IMO. Management HAS let Shareholders down (there I said it ...happy ?....actually I have said it many ...more  
Comment by hmmmmmmmm on Jan 30, 2023 6:25pm
We have clear, historic numbers to base future enrollment on. I know you'd rather ignore those numbers and "facts". Instead try and sell "possibilities", or be "willing to see what happens", but those don't replace the "facts". This management has shown us what they are able to enroll. They've added sites, added SOFA scores- but enrollment ...more  
Comment by daviking on Jan 30, 2023 5:17pm
MM, You assume everyone has money like you! I'm retired and don't have any spare money to average down. But I have been able to transfer shares 'in kind' into my TFSA since the price has reached previous low levels at different times over the last few years. Now they are tax free! So a 50% increase?? If it ever increases! Speaking of which, what kind of tax losses (credits in a ...more  
Comment by mercedesman on Jan 30, 2023 5:34pm
Careful.   If Spectral goes to zero (as Hmmmmmm and BSW and treebird think) then you will not be able to net the loss against other non-TFSA gains.  But, I'm quite positive on the eventual outcome, and so have a smattering of shares in my TFSA myself. I haven't looked lately but a few years ago the tax loss carryforwards were about $ 80M.  Probably now closer to ...more  
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