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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Probosciseson Nov 04, 2022 9:10pm
272 Views
Post# 35075042

RE:RE:RE:Could the volume here get any lower???????

RE:RE:RE:Could the volume here get any lower???????

The GOBLET trial is for four different types of gastro-intestinal cancer, including pancreatic cancer. The trial design envisions a total of 55 total patients for all four GI cancers, of which 12 were supposed to be for pancreatic cancer. We don't know how many patients have so far been enrolled in the pancreatic arm or when they were enrolled. 

The GOBLET trial was expected to run from 2022 to 2027. Given that almost 1/2 of the total 55 patients were already enrolled by the end of October this is "suggestive" of encouraging results.  I would expect that at least 6 patients have been enrolled in the pancreatic arm, but likely more based on the need for effective pancreatic therapy and the likelihood that the positive initial results encouraged doctors to recommend this clinical trial arm and patients to want to be part of it. But hey, I'm only guessing. Hopefully the next few weeks bring more clarity. 

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