Oncolytics Biotech Inc T.ONC

Alternate Symbol(s): ONCY

Healthcare Biotechnology

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.

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Oncolytics Biotech Inc

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Post by Noteableon Feb 04, 2024 5:07pm

244 Views

Post# 35862103

Quora Asked : What is the best treatment for pancreatic canc

Dr Harsh Shah

Gastro, Liver, Pancreas & Cancer Surgeon at Apollo Hospital , Ahmedabad (2017–present)Author has 74 answers and 19K answer viewsJan 14

Pelareorep and FOLFIRINOX Chemotherapy: A combination being studied for metastatic pancreatic cancer, especially in patients who haven't previously received cancer treatment. This approach includes assessing the safety and efficacy of the therapy.
pIC-based Treatment: Research in mice shows that a method involving polyinosine-polycytidylic acid (pIC) significantly extends life by enhancing the immune system's response to cancer cells. This approach is being studied for its potential in treating multiple cancer types.
Chemotherapy Combinations: Clinical trials are exploring various combinations, such as gemcitabine with erlotinib or capecitabine, to determine the most effective treatments for pancreatic cancer.
Precision Medicine and Multidisciplinary Care: Emphasizing the importance of personalized treatment plans, genetic and biomarker testing, and the involvement of a comprehensive healthcare team, including various specialists, to provide the best care for patients.
Immunotherapy and Biological Therapies: Focus on developing treatments that specifically target pancreatic cancer cells, including using pancreatic cancer vaccines in clinical trials to make cancer cells more vulnerable to the immune system.

Dr Harsh Shah

Gastro, Liver, Pancreas & Cancer Surgeon at Apollo Hospital , Ahmedabad (2017–present)Author has 74 answers and 19K answer viewsJan 14

Pelareorep and FOLFIRINOX Chemotherapy: A combination being studied for metastatic pancreatic cancer, especially in patients who haven't previously received cancer treatment. This approach includes assessing the safety and efficacy of the therapy.
pIC-based Treatment: Research in mice shows that a method involving polyinosine-polycytidylic acid (pIC) significantly extends life by enhancing the immune system's response to cancer cells. This approach is being studied for its potential in treating multiple cancer types.
Chemotherapy Combinations: Clinical trials are exploring various combinations, such as gemcitabine with erlotinib or capecitabine, to determine the most effective treatments for pancreatic cancer.
Precision Medicine and Multidisciplinary Care: Emphasizing the importance of personalized treatment plans, genetic and biomarker testing, and the involvement of a comprehensive healthcare team, including various specialists, to provide the best care for patients.
Immunotherapy and Biological Therapies: Focus on developing treatments that specifically target pancreatic cancer cells, including using pancreatic cancer vaccines in clinical trials to make cancer cells more vulnerable to the immune system.