RE: animal trialToday's news as I understand it is not related to what pfizer is doing with their animal trials.It is not known yet as to whether pfizer will actually be releasing any results soon,but my understanding is that they are still spending lots of money in this regards.
Onc has stated that they want to procede with trials involving systemic administration. Phase 1 trials dealt with direct tumor injection which is basically what they would then be limited to for the phase 2 with the prostate.
This is probabally one reason they are treating patients with early stage prostate cancer that hasn't metastiszed yet,but I believe that later trials will involve both direct tumor injection in association with systemic administration.
As for the glio,pre-clinical and phase 1 in the animal studies shows that the reo-virus appears to spread past the original tumor and treat any spread or metastisis.
Inthno