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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

Bullboard Posts
Comment by toinv261on Apr 11, 2014 11:32am
154 Views
Post# 22439969

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:INTERESTING ARTICLE RE LIPID MANAGEMENT , DOSING START

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:INTERESTING ARTICLE RE LIPID MANAGEMENT , DOSING START Hi Sanfran. Your posts are always excellent  because they explore the possibiities.

(is there a spell check on this site?).

However, I really do wonder about the valuation assumptions regarding the IPO value of Zenith being dragged down by the negative "brand equity" of rvx-208 - perceived broken promises. Well, the only broken promise (or hope for all) was the .6% plaque regression -  apparently an ill conceived end point.

From what I understand from biotech (he or she) did not agree with this criteria from the beginning. We know the MACE has to be replicated and if it replicates the impact on valuation is huge.

So now, on rvx-208 we have great scientific results...but the RVX brand reputation remains tarnished.

We all seem to assume that the near miss (remember it achieved a .4% regression)  drags down Zenith. I recognize that the boards and management are the same between RVX and Zenith.  

However, epigenetics and 208 are 2 separate pursuits. If Zenith can get some scientific wins out there (as they seem to have done in the lab) there should be the possibility to manage a successful IPO or 2 or 3 or 4.

For example, there could be the options of separating the brands completely. If RVX is a drag on Zentih there should be a complete perceptual separation. Websites should not be linked. They should completely unlink. 

Zenith could quickly develop an independent positioning. A new board could be appointed. New scientific faces could be put in place.

Obviously, these are very talented scientific people and their brand reputations should be maximized.

Challenge the assumptions!
Cheers
Toinv :)


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