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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

Bullboard Posts
Comment by toinv261on Jul 24, 2015 12:30pm
116 Views
Post# 23957173

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:and meanwhile back in china hepa is still not trading...

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:and meanwhile back in china hepa is still not trading...Hi prince. This is a message from hoity toity fraudster pumper dumper and whatever stupid nonsense you say.

Some of your posts lately have actually raised some important issues.

I am long on RVX because of the science but with the points raised about the ASSURE trial I am beginning to wonder. It seems to me that there could be a few perspectives;
  1. It could be that Dr Wong and his team have a good understanding of the science of rvx-208 and it's proven impact on significantly increasing ApoA-l (functional HDL).
  2. However, it seems that they have limited experience with clinical trial design.
  3. It also seems that they do not understand the FDA and/or do not have good relationships with them.

The Cleveland Clinic debacle also suggests RVX is missing resources regarding protecting the integrity of their trials.
  1. Sloppiness regarding trial compliance.
  2. What appears to be irresponsible statements by Dr Stephen Nicholls.
  3. Powering the study at 85%.
  4. Doing a 26 week trial.
  5. PAV as the primary end point.

Some of this is probably related to funding and other aspects seem to be related to how they understood the science of rvx-208 at the time.

I sometimes wonder if their sloppiness and tardyness is because they are all extremely well paid and secure because billionnaires tend to keep funding them? It sure makes one wonder doesn't it?

But also, the 26 week trial and the powering at 85% suggest that while rvx-208 is probably very effective, they over-estimated it's impact in the short term (and now have paid the price).

Don is clearly a liability when it comes to the undervaluation of the share price. It (the share price) should be much higher at this stage but his gaffs in over promising and under-delivering have dramatically reduced his credibility.

So prince, my question to you is
  1. "do you think there is any merit what-so-ever in the scientific and medical potential of rvx-208?".
  2. My second question is why is an important person like you bothering to post about RVX?
  3. Is your goal to protect fools like me who believe in the science? Are you essentially an ombudsman?

For a number of months I was giving Don the benefit of the doubt because of the tremendous progress that has been achieved over the past 2 years but lately he is back to his same old frothing at the mouth and not delivering.

I hope to be proven wrong and that BETonMACE phase lll will be approved by the FDA and that RVX will provide a clear statement about the BETonMACE phase lll trial approval in the EU.

I remain excited about the start of trials in China, Taiwan, Hong Kong and Macau.

So prince, please let all of us know the reality.
Cheers
Toinv    :)


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