RE:RE:RE:RE:RE:RE:RE:RE:BiotechI would suggest that the pre-portal vein top-up results were pretty great. Keeping a brittle diabetic's blood sugar level within a range that excludes hypo/hyperglycemic events is a success. A first-in-world success. Hyperglycemia causes all of the horrible long term side effects of the disease. Hypoglycemia can result in a coma or death and is the reason diabetics often keep their daily blood sugar levels too high. Avoiding these events would materially change life expectancy and quality of life. Given that the Edmonton Protocol is the standard of care for islet transplantation, it's no surprise it was done. It appears to me that they are getting quite close to a functional cure without a top-up. That would be the holy grail.