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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. It blocks viral entry into host cells while preserving normal immunologic function. The Company is also investigating an intramuscular method of administration of Trogarzo. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy.


TSX:TH - Post by User

Bullboard Posts
Post by Thao977on Oct 03, 2018 11:45am
164 Views
Post# 28737698

Pharmacokinetic Profile of Trogarzo™ Presented at IDWeek

Pharmacokinetic Profile of Trogarzo™ Presented at IDWeekMONTREAL, Oct. 03, 2018 (GLOBE NEWSWIRE) -- Theratechnologies Inc. (Theratechnologies) (TSX: TH) is pleased to announce that pharmacokinetic data from the pivotal phase III clinical trial for Trogarzo (ibalizumab-uiyk) injection will be presented tomorrow at IDWeek in San Francisco. Data to be presented conclude that the FDA-approved dosing regimen of 2,000 mg loading dose followed by an 800 mg maintenance dose every two weeks is enough to support high levels of CD4 receptor occupancy and drug concentration above therapeutic level. The data is derived from the pivotal TMB-301 study, an open-label 24-week, phase III clinical trial conducted in 40 heavily-treatment experienced patients with multidrug resistant HIV-1. Results from the TMB-301 clinical trial were published in the August 16, 2018 edition of the New England Journal of Medicine. IDWeek is one of the largest conferences in the field of infectious diseases and is attended by some of the worlds key opinion leaders in the field of HIV. Being able to present additional evidence about the efficacy of Trogarzo at such an important venue is key towards developing the full potential of this crucial tool in the fight against HIV, said Luc Tanguay, President and CEO, Theratechnologies Inc.
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