RE:To better understand the complexity of ADCsI never took Chemistry! Quite complex, but another take on it is that they have advanced the science on each part at an amazing clip. Given time, they seem to find novel ways to overcome problems. It is complex and I guess that's why those Trodelvy improvement numbers, despite being fairly small, are really a big deal in the science. Let's hope the UMontreal guys understand their technology enough to modify and overcome any issues. I suppose Annabi and Belieuve woudl still be available for consult if needed.