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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. It blocks viral entry into host cells while preserving normal immunologic function. The Company is also investigating an intramuscular method of administration of Trogarzo. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy.


TSX:TH - Post by User

Comment by SPCEO1on Jun 02, 2021 10:55am
111 Views
Post# 33310523

RE:Taimed's Conference May 31 of 2021

RE:Taimed's Conference May 31 of 2021Thanks again for your Taimed update.  Please see my responses in red below:

stock38 wrote:
Dear all

Is there anyone who can tell me the reason why the sales of Trogarzo is so bad. I have some guesses and do not know right or not. Would appreciate to have your comments and instructions.
When TH signed the deal with Taimed, they said at that time they expected sales of Trogarzo to be about equal to those of Egrifta. Only later did they change their mind and indicate that sales would be much greater than Egrifta's sales. The research that led TH to increase their sales forecasts was clearly very flawed. I do think they actually believed what they were saying as we did not see any insider selling at the top in May of 2018 and they likely would not have issued a convertible at that time if they did not believe what they were forecasting. The former head of sales did blow out most of the stock she owned a few months before the stock hit its peak (and well below the peak level it reached shortly thereafter) so perhaps she knew the sales forecasts had a good chance of being inaccurate. But, to my mind, the sales of Trogarzo were not bad, the upgraded forecast for demand of Trogarzo was what was bad.  
 
1. Both Taimed and TH said loudly at the beginning that Tro.is a 
    life saving drug  about 10000 to 15000 people are waiting it to 
    save lives. But the truth is that these people did not die without
   Tro. They actually can use current drug other than Tro.and still
   live well (maybe no well owing to the side effect of the drugs
   they were using). So this lifesaving disclosure is over 
   exaggerated or only kind of propaganda anyway( in this case
   the blame should be put mainly on Taimed who is the 
   procducer.
The blame is TH's not Taimed's. They are the ones who came up with that unrealistic forecast. Clearly, the IV aspect was a factor in the drug not being used as expected and we will see just how big a factor that is when the IV Push becomes available and then the IM version. But doctors were happy to keep adjusting their MDR patients old medications that were not working as well as they could, but well enough apparently, rather than switch those patients onto Trogarzo, which almost certainly would ahve been better for those patients.

2. Most MDR patients were underprivileged groups. Maybe 
    already lost their jobs and live miserably , so they can not buy
    insurance to cover Tro. If they apply to social assistance , they
    have to struggle to get permission which is no easy
    cause the budget is limited. In short , Tro.is good but the
    patients could not afford it. So the good efficacy means little for
    customers. The sale prospect is very dark it has few chance to
    go further.
What you are suggesting here is not really accurate. Indigent MDR patients can easily recieve the medical care they need via MedicAid. The budget is not limited and drugs like Trogarzo are covered. The problem with these type of patients is they just are so zoned out on drugs or mental health problems that they do not go to the doctor to get a prescription or, even if they do, they don't show up for their appointments. You may remember that TH took account of this in their early projections about the market size but I am not sure what they did with this group in the revised market projection.  
3. TH was unable to promote Tro. either because of their sale
    force or unproper strategy or both. In this case people may
    wonder if NASH project develops well, can they sell it well .
    Of course they can sell loyalty to others, that is another story.
It is common to blame the sales force or the sales management when a drug comes up short of its expectations but I suspect this is rarely accurate. If a drug fits a need, it sells regardless of the quality fot he sales force or the techniques used to market it. Those things help or hurt on the margin but rarely does a bad drug sell well because of great salespeople or clever marketing strategies. In Trogarzo's case, the doctors of the MDR patients just did not see a need for it for most of their MDR patients - only the most deperate got the drug. 
4. Now Taimed and TH are developing IV push and IM push. Do
    these two kinds  of injection really help sales a lot or just let
    patients have more options.
Time will tell. I believe these new versions will help some but not enough to make a huge difference in how you view Trogarzo's prospects. Even if Trogarzo sales doubled because of these new forms of drug administration, I doubt this would push either TH's stock or Taimed's stock back to its previous highs. But there should be some positive impact from these new versions.
5. TH made some payments to Taimed with their shares. I do not
    know exactly how much shares Taimed has . But I once asked      CFO of Taimed , why they did not charge TH with cash. He
    told me Taimed also paid their loyalty fee to other firms
    with shares and finally they got five times profits because
   Taimed shares went  high. Since Taimed was so confident
   about Tro. They even issued a statement that permit their staff
   have the right to buy Taimed's share at the price
   of  NT$180/share.The report showed that both CEO and 
   CFO bought many shares at this price(they do not sell till
   now). And now since the sales of Tro.is so frustrating that TH
   and Taimed's share plunged and plunged heavily. Right now
  Taimed's price is only NT$70 and the statement  became a
  sad joke
Taimed probably still owns the TH shares they have received but I cannot say so for sure. It may well pay off quite nicely for them if TH's cancer and/or NASH programs grab the attention of investors. 
6. I ho not know exactly how much shares of TH Taimed has.
    But the CFO told me once that if TH increases C$1.--, Taimed
    will benefit about 45 millions Taiwan dollars . so these two
    companies really bind together. You can imagine that Taimed
   already lost lot of money in TH’s share.
I can't remember the prices they got the TH shares at but they might not be at a loss at all or it may not be a large loss if there is a loss at this time. I am prettys ure they got the shares at good prices. Certainly the first tranche of shares they got when the deal was origianlly announced were priced quite low.

Thanks for your attention for reading this long letter
    Stock 38 from Taiwan
 
 



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