NASH NITs vs Biopsy discussion https://surfingnash.com/s2e36-ilc2021-wrap-up-big-issues-key-takeaways-remaining-issues/
This conversation is great. You can skip the first 5-10mins of folky stuff (don't be put off by it).
This is a bunch of academics, clinician and industry people.
The NIT vs Biopsy discussion is great. The extraordinary frustration with the regulators lack of movement away from biopsy is real. The belief that NITs (non-invasive tests) are ready to take over from biopsy is almost there. Presumably with a further meta-analysis of all the recent (failed) trials might be all that is needed to get these things over the bar. Seems like most of the NASH community is ready to move on but the regulators remain the roadblock. I'm pretty convinced external advancements like this would be great for THTX's program. If it had happened in 2020 we would be in a better position. We are looking at internal changes that might improve the company but externals could also have a big impact.