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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. It blocks viral entry into host cells while preserving normal immunologic function. The Company is also investigating an intramuscular method of administration of Trogarzo. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy.


TSX:TH - Post by User

Post by scarlet1967on Nov 26, 2021 8:46am
205 Views
Post# 34168013

Not cheap but effective

Not cheap but effective

Preparations for resistant virus strains

For patients whose viruses are resistant to other active substances, further drugs from new substance classes have been approved: The first tablet attachment inhibitor fostemsavir - commercial name Rukobia - and the first monoclonal antibody: The entry inhibitor ibalizumab - trade name Trogarzo - is administered every two weeks as an infusion. It blocks the CD4 receptors on human T cells and thus prevents the pathogen from entering these cells.

"You now have a quite extensive range of antibodies that are extremely effective," says Kirchhoff. However, they have a very high price: The Institute for Quality and Efficiency in Health Care (IQWiG) put the annual costs for trogarzo therapy at about 120,000 euros in January.

 

https://www.welt.de/wissenschaft/article235285634/Zahl-der-AIDS-Toten-hat-sich-in-den-letzten-zehn-Jahren-halbiert.html

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