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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. It blocks viral entry into host cells while preserving normal immunologic function. The Company is also investigating an intramuscular method of administration of Trogarzo. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy.


TSX:TH - Post by User

Comment by jfm1330on Apr 13, 2022 4:45pm
131 Views
Post# 34601811

RE:RE:RE:RE:RE:RE:Quick Summary

RE:RE:RE:RE:RE:RE:Quick Summary To put it in a nutshell, I was very annoyed to hear them talking about TH1902 at 300 mg/m2 in humans allowing 10 times more docetaxel in cancer cells than the recommended 80 mg/m2 of docetaxel alone, as if it was a reality. If it's a reality you should have clear efficacy data on humans and not say we will have to wait until phase Ib to see that. Add to that the fact that some patients got at least two cycles at 420 mg/m2. So according to their extrapolations, that would mean those patients got 15 to 20 times the concentration of docetaxel. They should stop talking about the animal data in relation with human patients until they have clear efficacy signal and proof of concept, by that I mean clear tumor shrinkage. That's it.
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