RE:POC The obvious scenario is it could pass on efficacy and fail on safety. No evidence of that yet though. There are maybe a dozen important things it needs to pass on and any of them could lead to ultimate failure. But really it's a step-by-step process and we are atm investing in the next step of 2 responders from 10 with a continuing manageable safety profile. That would be a good base to build from. I think we can now think that their definition of PoC is 2 from 10, that's the immediate target. Even with that in hand you're still not looking at assured success, I'm sure people will want to try to apply a ORR to that early data but if the drug is a good one then THTX should be able to improve on whatever comes out of these Ph1 trials and nudge those numbers up.
stockman75 wrote: What are chances TH1902 does not work but yet they establish POC? Is that an unlikely scenario? Hoping the keys didn't get jammed in the cancer door.