They filed the WO patent in February and it was published this month. Cancer stem cells as per latest research are present in various types of cancers including:
Breast, Colon, Ovary, Pancreas, Prostate, Melanoma, Multiple Myeloma, Non-melanoma skin cancer…
Although this research is early in the process it seems if and when they can duplicate the results in humans it can add significant value to the potential treatment against metastatic cancers.
From the patent application:
“Nearly all current cancer treatments focus on de-bulking tumors without targeting the most dangerous cells in the tumor: cancer stem cells (CSCs). CSCs are responsible for the spread of cancer cells throughout the body, the growth of tumors, cancer’s resistance to chemotherapy, and the recurrence of tumors after treatment or surgical removal, notably through their ability to arrest in the GO phase, giving rise to new tumors. Because current treatments do not target the CSC population, they frequently lead to the rise of resistant tumors and continued cancer spread. Therefore, CSCs could be considered the most promising targets for cancer treatment. There is thus a need for the development of strategies for the treatment of cancer, and more particularly cancers associated with CSCs, for example to overcome tumor resistance to cancer therapy, and prevent/treat cancer relapse and improve survival in cancer patients.”
https://patents.google.com/patent/WO2022178634A1/en