Talen Energy Corp V.TLN

Primary Symbol: TLN

Talen Energy Corporation owns and operates power infrastructure in the United States. The Company produces and sells electricity, capacity, and ancillary services in wholesale power markets in the United States, primarily in PJM and WECC, with its generation fleet principally located in the Mid-Atlantic region of the United States and Montana. The majority of its generation is produced at its zero-carbon nuclear and lower-carbon gas-fired facilities. Its generation capacity is 10,665 megawatts (MW). Its segments include PJM and Other. The PJM segment is engaged in electricity generation, marketing activities, commodity risk and fuel management within the PJM RTO or ISO markets and comprises Susquehanna and Talen’s natural gas and coal generation facilities. Its Other segment includes the operating and marketing activities of Talen Montana’s proportionate share of the Colstrip Units in the WECC market, the operating activities of Nautilus, and other development activities.

NDAQ:TLN - Post by User

Talen Energy Corp

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Post by Everswanon May 27, 2009 1:34am

109 Views

Post# 16018817

4601 - solving a two part equation

Check this out :
https://cbio.mskcc.org/cancergenomics/gbm/pathways/GBM_pathway_20080708.pdf

It's a map for molecular pathway.

ERK / MEK inhibition leads to cell cycle progression end. (ie hyper multiplication of cancer cell) which if inhibited equates to SD (stable disease).

This poster clearly shows this https://www.thallion.com/docs/publications/25.AACR09-Nadia-Web.pdf

Now, 4601 also inhibits Pi3k and AKT, which stop cell survival and promote cell autodestuct mecanism (Apoptosis).

https://www.thallion.com/docs/publications/20.AACR2008-1485.pdf

So, we should see tumor regression...

Combining 4601 with another apoptosis agent could generate significant tumor reduction and this cocktail could pretty much wipe out cancer cells...

Combining 4601 with chemo agent... or another EGFR...

Now, imagine 232 and 4601 combinaison...

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