RE:$tltff The FDA wants an option that has rates better thenThis patient population is elderly, fragile, who knows why they don't always have a CR at 90 days. 1433 has a log 3 kill rate in the test tube. If I were a NMIBC patiet I'd give it a try, certainly if they can get the 90 day CR % up into the 60s. IF I were then NR I'd try it again at the next 90 day period. Especially if I had a PR....
The safety profile is so low on this I can spend a few unfomfortable hours every 3 months until I get to CR. Maybe this will buy some patients extra time w/o losing their bladders?
I think the final NMIBC 90day CR will at least be in the 50s but probably better and into the 60s.
For other Cancers with less complicated dosemetry/treatment issues possibly higher %s.