RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:Maintenance DosePandora... the 12 undertreated patients are confusing almost everybody, but there is something that should help us, the next Dec 2022 CR% results.
The FDA said that for BTD, TLT need 20 to 25 patients treated with 66%CR.
In Dec 2022, out of the 28 patients left(33-5), 18 will be optimized patients that have completed the 450 days(Dec 2022) + 2 CR from phase1b(3Q2021 News Letter).
And these 18 optimized patients have a CR% potential of 94.4%(3Q2021 News Letter).
These 18 optimized patients (Phase2) + 2CR( Phase1b) patients could boost the CR% by a few points(at least over the 66%CR needed for BTD).
The above could explain why TLT is talking about Jan 2023 for a BTD,TLT could be waiting for these 18 optimized patients 450 days CR% results(Dec 2022).
Dec 2022 CR% could provide us with the catalyst that we are looking for.
Pandora wrote:
Wildbird1 in a sports mode when a person sets a record but it happens to be because of some circumstance or situation that is not considered normal then the record gets an * beside it. In our case
it seems our first eight patients should be asterisked as long as they are part of the database. :-))
It seems whether we have 41 or 71 or 101 in the database then those 8 undertreated patients will reflect negatively on the total result -- although the higher the number gets the less influence, but always a little negative bump. Negligible at some point I guess.